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Over half of eligible Americans have best1 a COVID-19 vaccine, and many have best1 common side effects - things like sore arms, maybe a fever. But some people say they have also had changes to best1 menstrual cycles. NPR's Geoff Brumfiel investigates. GEOFF BRUMFIEL, BYLINE: Katharine Lee is an anthropologist at Washington University School of Medicine best1 St.

BRUMFIEL: Like a lot of people, she wondered about the side effects she might have - headaches, fevers, things like that. But after getting the shot, she experienced something she definitely was not expecting - a change to her period. LEE: I'm on the Best1 IUD, so I normally don't experience a period.

And so I had breakthrough best1 and cramping, which for me is really, really unusual. Best1 The bleeding she experienced was spotting, not serious but uncomfortable. So she reached out to her colleague Kate Clancy, an anthropologist at the University of Illinois.

It turned out Clancy had experienced an unusually heavy period after her best1, and best1 had a best1 large Twitter following. KATE CLANCY: I just best1 to ask, and I did not anticipate it blowing up best1 the extent that it has. CLANCY: A lot of best1, a lot of Instagram DMs and a lot of tweets of people who are, like, just best1 their souls to us. BRUMFIEL: Clancy and Lee put together a survey for people to record their experiences.

So far, they've had over 140,000 responses. Many are reporting heavy flows, but others have seen changes as well. CLANCY: We started hearing a lot best1 breakthrough bleeding from people on pfizer johnson reversible contraception, people on gender-affirming hormones and postmenopausal people by publishing information packed articles you ll soon enjoy were years and years out from their last period, sometimes decades out.

BRUMFIEL: These stories are important, but they don't prove a connection to the vaccines. For one thing, Katharine Lee says they're told voluntarily by people who want to share their best1. BRUMFIEL: In other words, this is just a small fraction of the many tens of millions of people who've had a shot.

And many have not reported problems. In fact, vaccine manufacturers and the FDA all say they do not currently see evidence that best1 shots are causing any changes to menstruation. Kathryn Edwards is a physician at Vanderbilt University. She sits on an independent data monitoring committee for the Pfizer vaccine. It's a paid position.

BRUMFIEL: But Edwards says if the changes to menstruation are relatively minor, they might be missed. Participants best1 clinical trials are handed a checklist to ask about minor side effects like headaches or those sore arms people get.

EDWARDS: There aren't any queries to say, are your menstrual periods irregular. You know, are best1 - is your flow heavier. BRUMFIEL: In fact, best1 Centers for Disease Control and Prevention tells NPR it's now reevaluating its vaccine safety data to best1 whether it might be possible to spot any best1 menstrual issues that they would have overlooked before.

Best1 Riley best1 a doctor and chief of obstetrics and gynecology at New York-Presbyterian Weill Best1 Medical Center.

She says for anyone worried about all this, the data that's out there framework 4 actually best1 clear.

LAURA RILEY: You need to get vaccinated. The best1 of getting COVID-19, especially with rising cases due to this variant, are so much worse than missing a best1 or having one or two that are heavy. BRUMFIEL: At the same time, she best1 those who menstruate have a right to know whether a vaccine could best1 an influence.

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