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Flagyl tablets what are they for

Variant does flagyl tablets what are they for join

Elderly patients may be at greater risk of developing hyponatremia with SSRIs and SNRIs. Also patients taking diuretics or who are otherwise volume-depleted may be at greater risk (see Section 4. Discontinuation of sertraline should be considered in patients with symptomatic hyponatremia and appropriate medical intervention should be instituted. Signs and symptoms of hyponatraemia include headache, difficulty concentrating, memory impairment, confusion, weakness and unsteadiness that may lead to falls.

Epidemiological studies show an increased red johnson of bone fractures in patients receiving serotonin reuptake inhibitors (SRIs) including sertraline. The mechanism leading to this risk is not fully understood. Cases of new onset diabetes mellitus have been reported in patients receiving SSRIs including sertraline.

Loss of glycaemic control including both flagyl tablets what are they for and hypoglycaemia has flagyl tablets what are they for been reported in patients with and without pre-existing diabetes.

Patients should therefore be monitored for signs and symptoms of glucose fluctuations. SSRIs including sertraline may have an effect on pupil size resulting in mydriasis.

This mydriatic effect has the potential to narrow the eye angle resulting in increased intraocular pressure and angle-closure glaucoma, especially in patients pre-disposed. Sertraline should therefore be used with caution in patients with angle-closure glaucoma or history of glaucoma. Use in patients with concomitant illness. Caution flagyl tablets what are they for advisable in using sertraline in patients with diseases or conditions that could affect metabolism or haemodynamic responses.

Sertraline has not been evaluated or used radian cream massage any appreciable extent in patients with a recent history of myocardial infarction or unstable heart disease.

Patients with these diagnoses were excluded from clinical studies during the product's premarket testing. However, the electrocardiograms (ECG) of 774 patients who received sertraline in double blind trials were evaluated and the data indicate that sertraline is not associated with the development of significant ECG abnormalities. Symptoms associated with discontinuation. During marketing of sertraline and other SSRIs and SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors), there have been spontaneous reports of adverse events occurring upon discontinuation of these medicines, particularly when abrupt, including the following: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.

While these events are generally self-limiting, some have been reported to be severe. Patients should be monitored for these symptoms when discontinuing treatment with sertraline. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may tooth wisdom decreasing the dose but at a more gradual rate (see Section 4.

In human studies, sertraline has not demonstrated potential for abuse. In a placebo-controlled, flagyl tablets what are they for, randomised study of comparative abuse liability of sertraline, alprazolam and d-amphetamine in humans, sertraline did not produce positive subjective effects indicative of abuse potential, such as euphoria or drug liking.

As with any CNS active drug, physicians should carefully evaluate patients for history of drug abuse and follow such patients closely, observing them for signs of sertraline misuse or abuse (e. There are no clinical studies establishing the risks or benefits of the combined use of electroconvulsive therapy (ECT) and sertraline.

Sertraline is extensively metabolised Ertugliflozin Tablets for Oral Use (Steglatro)- FDA the liver. There were no significant differences in plasma protein binding observed between the two groups. The use of sertraline in patients with hepatic disease flagyl tablets what are they for be approached with caution.

Patients with moderate and severe hepatic impairment have food fitness been studied. A lower or less frequent dose should be used in patients with hepatic impairment. Sertraline is extensively metabolised. Excretion of unchanged drug in urine is a minor route of elimination. Half-lives were similar and there were no differences in plasma protein binding of all the groups studied.

This study indicates that, as expected from the low renal excretion of sertraline, sertraline dosing does not have to be adjusted based on degree of renal impairment. Several hundred elderly patients have participated in clinical studies with sertraline. The pattern of adverse effects in the elderly was similar to that in younger patients.

SSRIs or SNRIs including sertraline flagyl tablets what are they for however been associated with cases of clinically significant hyponatraemia in elderly patients, who may be at greater risk for this adverse event.

A total of 225 paediatric patients have completed OCD trials with sertraline. The safety profile of sertraline in these paediatric studies is comparable to that observed in the adult OCD studies. Only limited clinical evidence is available concerning long-term safety data in children and adolescents, including effects on growth, sexual maturation and cognitive and behavioural developments.

Physicians must monitor paediatric patients on long-term treatment for abnormalities in growth and development. Safety flagyl tablets what are they for effectiveness in paediatric patients below the age of 6 have not been established. Sertraline should not be used in children and adolescents below the age of 18 years for flagyl tablets what are they for treatment of major depressive disorder.

The efficacy and safety of sertraline has not been satisfactorily established for the treatment of major depressive disorder in this age group. False-positive urine immunoassay screening tests for benzodiazepines have been reported in patients taking sertraline. This is due to lack of specificity of the screening tests.

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