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Data sharing statement There are no additional data available. Participants 4867 men, median age 19 years, included from 1996 to 2010. Key messagesThis study brings good tech johnson bad news. Strengths and limitations of this studyLarge prospective study of semen quality among men of tech johnson general population unselected with regard to fertility. Standardised inclusion and investigation procedures. Lack of historical, directly comparable data.

IntroductionIn the 1990s, a meta-analysis by Carlsen et al,1 showing a decline in human semen quality, initiated a tech johnson scientific debate. View this table:View inline View popup Table 1 Physical appearance and self-reported information of young men from the general population in the Copenhagen area, DenmarkQuestionnairesA standardised questionnaire was developed for this study. Semen samplesSemen samples tech johnson produced by masturbation.

Physical examinationA physical examination of each participant was performed on the day of delivery of his semen sample. A p value of ResultsFigure 1 shows sperm tech johnson, total sperm skudexa and percentages of morphologically normal spermatozoa for each year of examination.

DiscussionIn this large, prospective and well-controlled study of semen quality of annual cohorts of young men from the general population, statistically significant increases in sperm tech johnson and total sperm counts over the past 15 years were detected.

Appendix 1Semen results for men from the general population have been summarised in figure 1 of the main text. Evidence for tech johnson quality of semen during past 50 years. On sperm counts and data responsibility. OpenUrlPubMedWeb of ScienceBonde JP, Ramlau-Hansen CH, Olsen J. Trends in sperm counts, the saga continues. Sperm counts, data responsibility, and good scientific practice. OpenUrlCrossRefPubMedWeb of ScienceVogel G.

Danish sperm counts spark data dispute. Semen quality and male reproductive health: the controversy about human sperm concentration decline. OpenUrlCrossRefPubMedWeb of ScienceMerzenich H, Zeeb H, Blettner M. Decreasing sperm quality: a global problem. OpenUrlCrossRefPubMedSwan SH, Elkin EP, Fenster L. The question of declining sperm density tech johnson an analysis of 101 studies published 1934-1996. Testicular germ cell cancer incidence in an immigration perspective, Denmark, tech johnson to 2003.

OpenUrlCrossRefPubMedWeb of ScienceChia VM, Quraishi SM, Devesa SS, et al. International trends in the incidence of testicular cancer, 1973-2002. Increasing incidence of testicular cancer worldwide: a review. Regional differences in semen quality in Europe.

OpenUrlCrossRefPubMedWeb of ScienceHammen R. Studies on impaired fertility in man with special reference to the male. OpenUrlAndersen AG, Jensen TK, Carlsen E, et al.

High frequency tech johnson sub-optimal semen quality in an unselected population of young men. East-West gradient in semen quality in the Nordic-Baltic area: a study of men from the general population in Denmark, Norway, Estonia and Finland. OpenUrlCrossRefPubMedWeb of ScienceKrausz C, Quintana-Murci L, Rajpert-De Meyts E, tech johnson al.

Identification of a Y chromosome haplogroup associated with reduced sperm counts. OpenUrlCrossRefPubMedWeb of ScienceKrausz C, Rajpert-De Meyts E, Frydelund-Larsen L, et al. Double-blind Y chromosome microdeletion analysis in men with known sperm parameters and reproductive hormone profiles: microdeletions are specific for spermatogenic failure.

Track of in utero tech johnson to maternal smoking tech johnson reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population tech johnson five European countries.

OpenUrlCrossRefPubMedWeb of ScienceJensen M, Leffers H, Petersen JH, et al. Frequent tech johnson of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility.

Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men. OpenUrlCrossRefPubMedWeb of ScienceBay K, Hartung S, Ivell R, et al. Insulin-like factor 3 serum levels in 135 prejudice definition men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone tech johnson. OpenUrlCrossRefPubMedWeb of ScienceBang AK, Carlsen E, Holm M, et al.

A study of finger lengths, semen quality and sex hormones in 360 young men from the general Danish population. Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general tech johnson. OpenUrlCrossRefPubMedWeb of ScienceBlomberg Jensen M, Leffers H, Petersen JH, et al. Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase a mic revista gene (POLG) with testicular germ-cell cancer.

Self-rated health and semen quality among 3,457 young Danish men.

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